After a strong funding year in 2024, the Porto Region saw a significant increase in disclosed investment volume in 2025, driven by a mix of early-stage activity, scale-up rounds, and late-stage capital injections. The year reflects the maturity of the ecosystem, with activity spanning from university spin-offs to international-scale ventures.
Below is a month-by-month overview of the most relevant funding events and ecosystem milestones across the year.
January
- Pathol.AI: AI-powered research platform improving pathology diagnosis; supported by EIT Health.
- Azitek: Porto-based 5G IoT company providing real-time asset visibility for logistics; supported by EIT Manufacturing.
- Game Scrobbler: Unified gaming data platform tracking playtime, achievements, and trends across multiple platforms; supported by EIT Digital Accelerator.
February
- BNanoTech: Nanoparticle technology for targeted central nervous system drug delivery; raised €12K in seed funding, with participation from XTX Ventures.
- Jscrambler: JavaScript protection and webpage monitoring technology company; raised $5.2M in growth equity, led by Iberis Capital.
- PFX Biotech: Porto-based biotech producing human milk proteins via precision fermentation; selected for a European acceleration program and raised €9.5M, reaching new milestones in research and production scale.
March
- SPACEO: Developing advanced technology for space debris removal; secured a seed round with participation from Portugal Ventures.
- Winalist: Porto-based startup boosting wine tourism in Portugal; raised €1M to enhance digital and on-site tourism experiences, supported by local investors and incubators.
- Immunethep – University of Porto spin-off focused on the development of vaccines against invasive E. coli infections; received $2M in non-dilutive funding from CARB-X to advance its peptide-based vaccine platform, strengthening Porto’s academic-driven biotech ecosystem.
May
- Tonic Easy Medical: Professional platform for medical doctors focused on improving clinical efficiency through secure case discussions and collaboration; backed by Armilar Venture Partners.
- knok: Digital health platform connecting patients, providers, and professionals through a Digital Front Door strategy; backed by Armilar Venture Partners in a Late VC round.
- SMARTEX.AI: Vila do Conde–based company developing machine-vision software and hardware for real-time textile defect detection; raised $40M, backed by AWS and H&M Group Ventures.
- ProGrow: Matosinhos-based enterprise software company focused on sharing operational results and best practices; raised $2.2M in Early VC, backed by Portugal Ventures, HCapital Partners, Lince Capital, and Touro Capital Partners.
June
- Seenergy: Developing furniture and household products integrating generative energy systems; supported by EIT Culture & Creativity.
- Sword Health: Global health scale-up connecting licensed physical therapists with technology; raised $40M in late-stage VC, pushing its valuation to €3.6B.
- PFX Biotech: Porto-based biotech producing human milk proteins via precision fermentation; raised €2.5M in seed funding, reaching a valuation between €10–15M.
July
- Reckon.ai: AI-powered computer vision platform enabling grab-and-go retail experiences; raised €5.1M in Early VC, with backing from Iberis Capital, Touro Capital Partners, and Alea Capital Partners.
- MobyFly: Zero-emission hydrofoil passenger boats reducing energy consumption by 70%; raised CHF 10.1M in Series A, reaching a valuation of up to €51M.
September
- Effizency: B2B energy services sales acceleration platform; secured an Early VC round with Touro Capital Partners and S317 Consulting (amount undisclosed).
October
- WiseWorld: Virtual world designed to simulate real-life scenarios for soft skills assessment and training; raised a seed round with AngelsWay.
- Curiouz: Marketplace for sustainable and vintage furniture; raised a seed round backed by AngelsWay.
November
- Seedsight: Porto-based agri-tech company tackling food waste with data-driven solutions; secured €1.78M in funding to scale operations and expand internationally.
December
- Coreflux: Porto-based real-time data integration platform enabling seamless connectivity across devices and systems; raised €1.2M in Early VC funding, with participation from NOS Portugal and Armilar Venture Partners.
- Cell4Food: University of Porto spin-off developing cell-based seafood solutions; raised €1.5M to advance cell-based seafood innovation.
Most of the information in this article is based on the data available on the Porto Ecosystem Map.
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